Ectomesenchymal chondromyxoid tumor (ECMT) is a rare tumor, exclusively arising in the anterior tongue. Thirty-eight cases have been reported in the English literature. It usually presents as a sessile protrusion and shows round to spindle cells embedded in myxoid to chondroid stroma. Tumor cells are almost always positive for polyclonal glial fibrillary acidic protein (GFAP). We report our experience in the recent treatment of a case of ECMT, the third case in 3 years. The mass in the anterior tongue revealed characteristic morphologic features of ECMT and the expression of polyclonal GFAP. Although ECMT should be differentiated from other mesenchymal tumors including myoepithelioma, its clinical, morphological, and immunohistochemical features enable its diagnosis, especially when pathologists are aware of it.
Glial Fibrillary Acidic Protein ; Myoepithelioma ; Tongue

Chordoid glioma is an uncommon low-grade tumor of the third ventricle with histologic features of a chordoma and immunolabeling for glial fibrillary acid protein. We present a rare case of a patient with a chordoid glioma of the third ventricle and review the literature regarding this tumor's clinical, radiological and pathologic aspects.
Chordoma ; Glial Fibrillary Acidic Protein ; Glioma ; Humans ; Third Ventricle

The pleomorphic xanthoastrocytoma is considered as a special subgroup of gliomas because of its distinctive characteristics regarding age, gross and microscopic features, and perhaps, most importantly, the relatively favorable prognosis despite of pleomorphism and bizarre giant cells in the microscopic picture. Because of rarity of this disease entity, we report a case of pleomorphic xanthoastrocytoma with a review of literature.
Giant Cells ; Glial Fibrillary Acidic Protein ; Glioma ; Prognosis

The pleomorphic xanthoastrocytoma is considered as a special subgroup of gliomas because of its distinctive characteristics regarding age, gross and microscopic features, and perhaps, most importantly, the relatively favorable prognosis despite of pleomorphism and bizarre giant cells in the microscopic picture. Because of rarity of this disease entity, we report a case of pleomorphic xanthoastrocytoma with a review of literature.
Giant Cells ; Glial Fibrillary Acidic Protein ; Glioma ; Prognosis

The pleomorphic xanthoastrocytoma is considered as a special subgroup of gliomas because of its distinctive characteristics regarding age, gross and microscopic features, and perhaps, most importantly, the relatively favorable prognosis despite of pleomorphism and bizarre giant cells in the microscopic picture. Because of rarity of this disease entity, we report a case of pleomorphic xanthoastrocytoma with a review of literature.
Giant Cells ; Glial Fibrillary Acidic Protein ; Glioma ; Prognosis

The pleomorphic xanthoastrocytoma is considered as a special subgroup of gliomas because of its distinctive characteristics regarding age, gross and microscopic features, and perhaps, most importantly, the relatively favorable prognosis despite of pleomorphism and bizarre giant cells in the microscopic picture. Because of rarity of this disease entity, we report a case of pleomorphic xanthoastrocytoma with a review of literature.
Giant Cells ; Glial Fibrillary Acidic Protein ; Glioma ; Prognosis

The pleomorphic xanthoastrocytoma is considered as a special subgroup of gliomas because of its distinctive characteristics regarding age, gross and microscopic features, and perhaps, most importantly, the relatively favorable prognosis despite of pleomorphism and bizarre giant cells in the microscopic picture. Because of rarity of this disease entity, we report a case of pleomorphic xanthoastrocytoma with a review of literature.
Giant Cells ; Glial Fibrillary Acidic Protein ; Glioma ; Prognosis

The pleomorphic xanthoastrocytoma is considered as a special subgroup of gliomas because of its distinctive characteristics regarding age, gross and microscopic features, and perhaps, most importantly, the relatively favorable prognosis despite of pleomorphism and bizarre giant cells in the microscopic picture. Because of rarity of this disease entity, we report a case of pleomorphic xanthoastrocytoma with a review of literature.
Giant Cells ; Glial Fibrillary Acidic Protein ; Glioma ; Prognosis

The pleomorphic xanthoastrocytoma is considered as a special subgroup of gliomas because of its distinctive characteristics regarding age, gross and microscopic features, and perhaps, most importantly, the relatively favorable prognosis despite of pleomorphism and bizarre giant cells in the microscopic picture. Because of rarity of this disease entity, we report a case of pleomorphic xanthoastrocytoma with a review of literature.
Giant Cells ; Glial Fibrillary Acidic Protein ; Glioma ; Prognosis

Recently, there has been considerable attention focused on the multipotent progenitor cells existing in ependymal and subependymal layer. However, almost all results have been derived from brain or injured CNS researches. So, the studies on the developmental characteristics of intact spinal ependymal layer have been relatively ignored. In the present study, we labeled rat spinal cord with nestin, bromodeoxyuridine (BrdU), and glial fibrillary acidic protein (GFAP) antibodies in order to track the differentiation and proliferative capacity of rat ependymal layer cells according to their developmental stages. At embryonic day 14 (E14), a number of cells in the spinal ependymal layer, especially constituting the alar and basal plates, showed extensive nestin immunoreactivities (ir). They also showed active proliferative capacities, because many nuclei of nestin-ir cells were also BrdU-ir. From postnatal day 0 (P0), nestin-ir cells were almost completely disappeared, and from P7, no nestin-ir cells could be detected. However, BrdU-ir nuclei continued to be identified until P14. These results suggested that the cells in the spinal ependymal layer retain their proliferative capacity until later stage of development. On the other hand, no GFAP-ir cells could be identified in the ependymal layer in our experimental period.
Animals ; Antibodies ; Brain ; Bromodeoxyuridine* ; Glial Fibrillary Acidic Protein ; Hand ; Nestin* ; Rats* ; Spinal Cord ; Stem Cells