No abstract available.
Female ; Female* ; Genitalia, Female* ; Humans ; Incidence*

We experienced six cases of aesthetic labioplasty since September of 1998 to April of 2000. We performed three cases of simple excision, one case of wedge resection and two cases of deepithelized reduction labioplasty. The patients wanted surgery for various reasons such as aesthetic discontent, poor hygiene, diminished self confidence, poor sex appeal and agonizing chafing and irritation. They were satisfied with resultant physical comfort from improved hygiene, relieved chafing and irritation and better sexual enjoyment.
Felodipine ; Female ; Female* ; Genitalia, Female* ; Humans ; Hygiene

No abstract available.
Female ; Humans

Sjogren's syndrome is a chronic autoimmune disorder due to lymphocytes infiltrations of the exocrine glands and is clinically characterized by dry eyes and dry mouth. Though Sjogren's syndrome can affect the nervous system, acute transverse myelitis is an extremely rare CNS complication that progresses rapidly, and requires early diagnosis and therapy. Here, we report a 49-year-old female who had primary Sjogren's syndrome that manifested itself as acute transverse myelitis. She presented with motor weakness and hypesthesia of her right lower extremity. During her first attack, MRI of the spine revealed high signal intensities on T2-weighted images in her spinal cord at the levels of C6 through T11. Symptoms improved after 5 days of intravenous methylprednisolone (1 g/day) therapy, but recurred 9 months later. She had another MRI which showed acute transverse myelitis involving the spinal cord at the levels of C2 to T8. Her symptoms remained well controlled with treatment consisting of 5 days of methylpredisolone infusion (1 g/day) and concomitant intravenous cyclophosphamide 750 mg every 4 weeks.
Female ; Humans

Spinocerebellar Ataxia Type 3 (SCA3) is a rare autosomal dominative disorder in which one of the neurodegenerative disorders is caused by a CAG repeat expansion on chromosome 14q32.1. The age at onset of disease is related to the size of the expanded CAG repeat. We present the prenatal diagnosis of SCA3 in a woman whose husband was known to carry an unstable CAG repeat expansion in the MJD gene. The diagnosis was made using PCR with a fluorescent probe for an expanded MJD allele. The normal ranges of (CAG)n of SCA3 are 14~38 repeats. The husband, who had a family history of SCA3, has an expanded allele of 69 CAG repeats with a normal allele of 27 repeats. His wife had two normal alleles with 26 and 32 CAG repeats. The fetus had two normal alleles with 26 and 27 CAG repeats; consequently, the baby was healthy. We report a case of prenatal diagnosis of SCA3 using a fluorescent PCR which is rapid and accurate.
Female ; Humans

PURPOSE: Menkes disease is an X-linked recessively inherited disorder caused by the mutation of the ATP7A gene encoding copper-transporting P-type ATPase. The phenotypic features are progressive neurological degeneration, mental retardation, loose skin, and vascular complications. Early diagnosis and treatment are very important for the prognosis of Menkes disease. Here, we describe novel mutations of the ATP7A gene and prenatal diagnosis by mutation analysis. METHODS: Five unrelated Korean Menkes patients were included in this study. They presented with depigmented wool-like hair, progressive neurologic deterioration, and hypotonia in infancy. Serum copper and ceruloplasmin levels were decreased. Brain magnetic resonance imaging revealed tortuous intracranial vessels. Mutation analysis has been carried out using cDNA from cultured skin fibroblasts or genomic DNA from peripheral leukocytes. Prenatal diagnosis was performed in two cases using chorionic villi samples or amniocytes. RESULTS: Four novel mutations have been identified from four different families; c.3511+1Gfemale heterozygote with p.S624_Q724del mutation of the ATP7A gene. CONCLUSION: We identified 4 novel mutations of the ATP7A gene. Prenatal diagnosis in families at risk is critical in order to choose preventive options including an early treatment with copper-histidine therapy or therapeutic termination. Most mutations of the ATP7A gene were frame-shift mutations and prenatal diagnosis has been successfully carried out.
Female ; Humans

There were few reports about the fluoride concentration in bone and osteoporotic women. This study was designed to evaluate the relationship between the urinary fluoride concentration and periodontal condition in osteoporotic old women. Twenty-eight postmenopausal women(Test group) and twenty-one premenopausal women(Control group) were examined. Bone mineral density(BMD) of lumbar spine(L2-L4) was measured by dual energy X-ray absorptiometry(DEXA). The urine samples were collected at early morning and determined with the help of a fluoride-specific electrode and Tisab-bufferd samples. The results were as follows. 1.The mean urinary fluoride concentration in test and control group showed statistically no difference. 2.The bone mineral density(BMD) of the spine in test group was significantly lower than control group(p<0.05). 3.The significant negative correlation was found between BMD level and age after menopause(p<0.001, gamma=-0.526). 4.The urinary fluoride concentration was not correlated with age, age after menopause and bone mineral density. 5.The urinary fluoride concentration was not correlated with periodontal condition.
Female ; Humans

In removing a huge abdominal mass, we often observe acute hemodynamic changes, For adequate anesthetic management we must carefully observe CVP, MAP, ECG and pulse rate ect. The authons report an an anethetic experience in the removal of huge a ovarian cystic mass. The patient was 29year old female. Under contianous monitoring of CVP, MAP, ECG, pulse rate and fluid administration, the patient tolerated the anesthetic period well. The total weight of the tumor mass was about 34kg, which waa composed of 30L cystic fluid and 4kg of solid maas.
Female ; Humans

Pseudomonas aeruginosa is an aerobic, Gram-negative bacillus present in water, soil, and plants. Pseudomonas aeruginosa does not belong to the normal skin flora, as the microorganism is unable to withstand dryness. Pseudomonas aeruginosa folliculitis, also known as hot tub folliculitis, can develop after exposure to contaminated water in heated swimming pools, whirlpools, and hot tubes or after diving suit dressing. We report a 30-year-old female with Pseudmonas aeruginosa folliculitis after exposure to a warm, moist environment.
Female ; Humans

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms affecting the gastrointestinal tract. The main sites for GIST are the stomach and small intestine but they can also occur in the rectum, albeit rarely. We report a 58-year-old woman who presented with hematochezia. Endoscopically, a submucosal tumor with mucosal ulceration was located approximately 2 cm from the anal verge. The pelvic CT and MRI scanning findings demonstrated a large low-density lesion with intraluminal growth from the lower rectum and an absence of tumor infiltrations to other organs. The patient underwent an abdominoperineal resection of the rectum. A histopathological examination showed fascicular proliferation of spindle shaped cells. The mitotic rate was more than 30 mitotic figures per 50 high-power fields. A immunohistochemical examination revealed most of the tumor cells to be positive for the c-kit protein, CD34 and SMA (alpha-smooth muscle action). The tumor was diagnosed as a GIST of the rectum.
Female ; Humans