Bei JIA ; Chao WU

Journal of Medical Postgraduates 2020;33(7):673-677

Coronavirus disease 2019 (COVID-19) has become a serious global public threat. With the progress of research, we have more comprehensive understanding of the COVID-19. Current advances on the etiology, transmission, clinical features, diagnosis and treatment of COVID-19, as well as the experience in the management of COVID-19 will be introduced in this article.

Yun-hu PAN ; Guang CHEN ; Zhi-hua WANG ; Guo-ji XIA ; Mao-zeng LIN ; Ji-qiu WEN ; Yuan-cheng HONG

Journal of Medical Postgraduates 2020;33(7):748-751

ObjectiveTo investigate the relationship between the levels of D-dimer and inflammatory factors C-reactive protein（CRP）and prognosis in patients with 2019 novel coronavirus-infected pneumonia（COVID-19）.Methods The clinical data of a total of 242 patients with COVID-19 who were treated in hospital from February 4th 2020 to February 18th 2020 were analyzed retrospectively. According to the classification standard,the patients with COVID-19 were divided into common patients(131 cases), severe patients（88 cases）, and critical patients（23 cases）. The difference between the levels of D-dimer and CRP in patients with pneumonia of different severity and clinical outcomes was compared and the correlation between D-dimer and CRP was analyzed.ResultsThe levels of D-dimer and CRP in severe and critical patients were significantly higher than those in common patients(P<0.05). The levels of CRP in critical patients were significantly higher than those in severe patients(P<0.05). These two indicator levels of patients who died of COVID-19 within 30 dayswere significantly higher than those who survived. Pearson correlation analysis showed that the levels of D-dimer were positively correlated with the levels of CRP(r=0.649，P<0.05).ConclusionD-dimer and CRP are highly expressed in severe and critical patients, and the severe abnormality of the two indicators in the early stage of COVID-19 predicted the poor prognosis. D-dimer and CRP have certain clinical value in evaluating the severity and prognosis of COVID-19.

Jin-hu SHI ; Li YUAN ; Shu JIANG ; Jun CAI ; Quan LIANG ; Zhi LI ; Xiao-li XU

Journal of Medical Postgraduates 2020;33(7):752-754

Based on the rapid development of COVID-19 epidemic, China has built Huoshenshan Hospital in Wuhan. This paper analyzes the matching degree between drug consumption in Huoshenshan Hospital and medicine prepared by the medical team in the early stage and the use of medicine in the first week after receiving the patients in Huoshenshan Hospital, and compares it with medicine carried by the medical team. With the novel coronavirus infection developing rapidly, the superior group has a tight schedule and a heavy task, and the preparation time before setting out is only 3 days, the matching degree of pharmaceutical supply can reach 60% within a short period of time, which can already meet the general clinical treatment needs. This paper analyzes the situation of preparing medicine in medical teams in the early stage, and provides experience for future medical teams to carry out the law again.